Simon Yona

Simon Yona was born in Glasgow, Scotland. He performed his PhD. under the direction of Professor Rod Flower FRS, St. Bartholomew’s Hospital (University of London). After completing his PhD, he joined the laboratory of Professor Siamon Gordon FRS at the Sir William Dunn School of Pathology (University of Oxford), studying adhesion-GPCRs in the context of macrophage and neutrophil signaling. In 2008, Simon received a FEBS Fellowship to work with Professor Steffen Jung at the Weizmann Institute of Science. His studies there focused on generating transgenic mice, to manipulate and fate map the mononuclear phagocyte system. To this end, he revealed the ontogeny and dynamics of circulating monocytes and resident macrophages under steady state. Furthermore, he demonstrated how classical monocytes undergo multiple transcriptional, phenotypic and functional changes at sites of angiogenesis. He returned to the United Kingdom and joined the Division of the Medicine at University College London (University of London). More recently, Simon moved his laboratory to the Hebrew University in Jerusalem. Work in his lab aims at understanding human mononuclear phagocyte biology, specifically, the developmental profile and their distinct functions in health and disease.